theory, each sperm) contained the entire embryo writ small, complete with limbs, liver and lungs. Stranger yet, this tiny embryo (which some microscopists claimed they could see) also contained eggs or sperm, each of which, in turn contained an embryo…and so on,
ad infinitum
. Each of Eve’s ovaries, by this reasoning, contained all future humanity.
Preformationism was an ingenious theory and won prominent adherents. Yet many seventeenth- and eighteenth-century philosophers, among them freethinkers such as Buffon and Maupertuis, preferred some version of the older theory of ‘epigenesis’, the notion that embryonic order does not exist in the egg or the sperm
per se
, but rather emerges spontaneously after fertilisation. At the time of the
querelle
, many thought that the preformationists had the better side of the argument. Today, however, it is more difficult to judge a victor. Neither the preformationists nor the epigeneticists had a coherent theory of inheritance, so the terms of the debate between them do not correspond in any simple way to a modern understanding of the causes of deformity or development. Preformationism, with its infinite regress of embryos, seems the more outlandish of the two theories, though it captures nicely the notion that development errors are often (though not invariably) due to somemistake intrinsic to the germ cells – the cells that become eggs and sperm – or at least their DNA. But the epigeneticists speak more powerfully to the idea that embryos are engaged in an act of self-creation which can be derailed by external influences, chemicals and the like, or even chance events within their dividing cells.
HOW TO MAKE A CONJOINED TWIN
What makes twins conjoin? Aristotle, characteristically, covered the basic options. In one passage of
The generation of animals
he argues that conjoined twins come from two embryos that have fused. That, at least, is where he thought conjoined chickens (which have four wings and four legs) come from. But elsewhere he suggests that they come from one embryo that has split into two.
To modern ears his notion of how an embryo might split sounds odd, but it is a sophisticated account, all of a piece with his theory of how embryos develop. Having no microscope, Aristotle knows nothing of the existence of sperm and eggs. Instead he supposes that embryos coagulate out of a mixture of menstrual fluid and semen, the semen causing the menstrual fluid to thicken rather as – to use his homely metaphor – fig juice causes milk to curdle when one makes cheese. This is epigenesis
avant la lettre
. Indeed, preformationism was very much an attack on the Aristotelian theory of embryogenesis and, by extension, its account of the origins of deformity. Sometimes, says Aristotle, there is simply too much of the pre-embryonic mix. If there is only a little too much, you get infants with extraor unusually large parts, such as six fingers or an overdeveloped leg; more again, and you get conjoined twins; even more mix, separate twins. He uses a beautiful image to describe how the mix separates to make two individuals. They are, he says, the result of a force in the womb like falling water: ‘…as the water in rivers is carried along with a certain motion, if it dash against anything two systems come into being out of one, each retaining the same motion; the same thing happens with the embryo’.
For Aristotle, the two ways of making conjoined twins bear on their individuality. He rules that if conjoined twins have separate hearts, then they are the products of two embryos and are two individuals; if there is only one heart, then they are one. The question of conjoined twin individuality haunts their history. Thomas Aquinas thought that it depended on the number of hearts
and
heads (thereby ensuring perpetual confusion for priests who wanted to know how many baptisms conjoined infants required). When twins are united by only by a slender cartilaginous band – the case
Under the Cover of the Moon (Cobblestone)